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We demonstrated the key transducing role of IL18R1 both in vitro (IL18R1 antibody treatment significantly reversed CXCL10-induced ovarian damage in in vitro-cultured ovaries) and in vivo (blocking CXCL10IL18R1 binding could very effectively rescue fibrosarcoma-induced ovarian damage)

The stained sections were analyzed using an Olympus Model BX41TF microscope and photographed using Olympus DP Controller

But when the mitochondria make energy, they also make reactive oxygen species (ROS), substances that can damage mitochondria and your cells, unless they are neutralized by antioxidants like glutathione 13